“Kalzium macht alles”. With this sentence, the physiologist L. V. Heilbrunn described
several decades ago what is still believed by many. The enormous attention this subject
has received in the past 15 years has generated a vast amount of information which
is helping us to understand how cells perceive and transduce a signal. This review
focuses on some recent aspects of Ca2+ research and the perspectives that they open for future studies. However, Ca2+ is not the only element involved in signal transduction and its action depends on
a complex network of signalling molecules, the role of which is discussed. Particular
attention is given to the parallels emerging between plant and animal signalling and
how we should explore them.
Calcium - calmodulin - Ins(1,4,5)P3
- protein kinases